Global

2024 HPCC Systems Community Summit

The 11th annual HPCC Systems Community Summit will kick off the week of October 7 with an exciting line up of speakers, sessions and engaging workshops. This year’s theme is Igniting Innovation and is free to attend for academia, industry and technologists. The purpose of the Summit is to gather engineers, data scientists and technology professionals to share knowledge and future roadmap plans for the open source HPCC Systems platform.

Despite significant investment, effective treatments for Alzheimer's disease (AD) have been elusive, necessitating improved quality and reproducibility of foundational laboratory evidence; to address this, AD-SOLES, an integrated workflow of automated tools and a publicly accessible interactive dashboard, has been developed to collect, curate, and visualize in vivo experimental evidence, enhancing evidence synthesis, tracking reporting quality, and aiding researchers in locating relevant data.
The study demonstrates that the peptide PHDP5, which inhibits dynamin-MT interaction, can rescue impaired endocytosis and synaptic transmission caused by tau in presynaptic terminals. When administered intranasally to Alzheimer's disease (AD) model mice, PHDP5 significantly improved learning and memory, suggesting its potential as a candidate for human AD therapy.
The study investigates the neuroprotective effects of hordenine against AlCl3-induced Alzheimer’s disease in rats. Results show that hordenine improves memory and cognitive functions, suggesting its potential to reverse oxidative stress and neuroinflammation associated with Alzheimer’s
Nurse practitioners and other health care providers can play a crucial role in implementing chronic disease management strategies and educating patients who are at risk for AD among African Americans and Hispanics.
Elsevier,

Energy Transport Infrastructure for a Decarbonized Economy, 2025, Pages 373-395

The chapter on district heating and cooling, which discusses the advantages of centralized heat distribution systems using various energy sources to support multiple users, aligns with UN SDG 7 (Affordable and Clean Energy) by promoting energy efficiency, reducing greenhouse gas emissions, and potentially lowering utility costs for users.
This content aligns with Goal 3: Good Health and Goal 13: Climate Action by exploring the relationship between mental health and climate anxiety in subjects of differing ages.
This study evaluated the behavioral, physiological, and molecular effects of social isolation (SI) in adult zebrafish, and whether the animals recover such changes after their reintroduction to the social environment. The results show that SI altered social behaviors, neural activity, and serotonergic and dopaminergic signaling in zebrafish, but these changes were reversed after the animals were reintroduced to a social context for 6 days.
Elsevier,

Climate Crisis, Energy Violence, Mapping Fossil Energy' s Enduring Grasp on Our Precarious Future, 2024, Pages xvii-xlix

This chapter advances Goals 13 and 16 by discussing how the book demonstrates “textbook” cases of energy violence using an empirical approach highlighting (1) spatial and temporal evidence and (2) ecological and societal impacts across global and local scales, including frontline communities.

Elsevier,

Encyclopedia of Renewable Energy, Sustainability and the Environment, Volume 1, 2024, Pages 497-508

This chapter relates to the energy transition and renewable fuels for global energy demands. UN SDG Goal 7

Pages