Global

N-type Mg3Sb2-based Zintl compounds have attracted considerable interest in recent years for their high thermoelectric performance. Mg3Sb2-based compounds inherently have p-type transport properties because of the presence of intrinsic Mg vacancies. Therefore, eliminating Mg vacancies and increasing the electron concentration are crucial for achieving high-performance n-type Mg3Sb2-based materials. The addition of excess Mg in the initial composition and the doping of chalcogens (Te, Se, and S) at the Sb site have been the primary methods used to date.
The current paper addresses the nature of epistemic injustice as it may be experienced by persons with dementia. We describe how theoretical models of stigma align with the current model of epistemic injustice through a consideration of the concepts of ‘stereotype’ ‘prejudice’ and ‘discrimination’ shared by the two models. We draw on current understandings of dementia-related stigma to expand understandings of the epistemic injustice faced by persons with dementia.
Alzheimer's disease (AD) is considered a polygenic disorder. This view is clouded, however, by lingering uncertainty over how to treat the quasi “monogenic” role of apolipoprotein E (APOE). The APOE4 allele is not only the strongest genetic risk factor for AD, it also affects risk for cardiovascular disease, stroke, and other neurodegenerative disorders. This review, based mostly on data from human studies, ranges across a variety of APOE-related pathologies, touching on evolutionary genetics and risk mitigation by ethnicity and sex.
Elsevier,

TrAC - Trends in Analytical Chemistry, Volume 112, March 2019

Plastics are a frequently observed component of marine debris and there is growing concern about microplastic (MP) ecotoxicity, and the impacts of additives, sorbed hazardous organic contaminants, heavy metals, and biofilm on MP surfaces. The relative importance of MP from different terrestrial and freshwater sources is poorly understood and limits our ability to develop best management practices.

With growing health risks from rising temperatures in the Global South, the lack of essential indoor cooling is increasingly seen as a dimension of energy poverty and human well-being. Air conditioning (AC) is expected to increase significantly with rising incomes, but it is likely that many who need AC will not have it. We estimate the current location and extent of populations potentially exposed to heat stress in the Global South.

Elsevier,

Materials Today Sustainability, Volume 3-4, March 2019

The built environment is responsible for large negative ecological impacts due in part to the vast amount of materials used in construction. Concurrently, construction and demolition activities result in vast amounts of materials being buried, burnt, and dumped. It is essential therefore to analyze the impact of building materials acquisition, use, and transformation on the ecosystems people inhabit and rely upon for well-being. Typically, this is examined in terms of material use, energy use, and emission of pollutants including greenhouse gases.

Altered synaptic structure and function is a major hallmark of fragile X syndrome (FXS), autism spectrum disorders (ASDs), and other intellectual disabilities (IDs), which are therefore classified as synaptopathies. FXS and ASDs, while clinically and genetically distinct, share significant comorbidity, suggesting that there may be a common molecular and/or cellular basis, presumably at the synapse.

There is a metabolic rift running through our economy and culture, and it is distracting our attention from care for the biosphere. To heal this rift, the diverse groups of people that make up humankind need a shared purpose that everyone can relate to and support. A strong candidate for that shared purpose is care for the bioregion—bioregioning—as an activity that creates value.

Elsevier,

Renewable and Sustainable Energy Reviews, Volume 101, March 2019

Research into alternative renewable energy generation is a priority, due to the ever-increasing concern of climate change. Microbial fuel cells (MFCs) are one potential avenue to be explored, as a partial solution towards combating the over-reliance on fossil fuel based electricity. Limitations have slowed the advancement of MFC development, including low power generation, expensive electrode materials and the inability to scale up MFCs to industrially relevant capacities. However, utilisation of new advanced electrode-materials (i.e.

Elsevier,

Handbook of Sleep Disorders in Medical Conditions, 2019, Pages 253-276

This chapter addresses goal 3 by providing an overview of sleep disorders in dementia.

Pages