Health and population

Health and population dynamics are intertwined, embodying an intricate relationship with significant implications on the Sustainable Development Goals (SDGs). Health is fundamentally at the center of these 17 global goals, aimed to transform the world by 2030. Specifically, Goal 3 endeavors to "Ensure healthy lives and promote well-being for all at all ages." It acknowledges that health is pivotal to human life quality, social cohesion, and sustainable development. Inextricably linked to this are the complexities of population dynamics, including growth rates, age structure, fertility and mortality rates, and migration patterns.

With the world's population projected to exceed 9.7 billion by 2050, the pressure on health systems will undoubtedly escalate. The demographic transition, with an aging population and an increasing prevalence of non-communicable diseases, poses new challenges for health systems globally. Additionally, areas with high fertility rates often overlap with extreme poverty, resulting in heightened health risks, including higher maternal and child mortality rates, malnutrition, and infectious diseases.

Moreover, rapid urbanization and migration present both opportunities and threats to health. While urban areas may provide better access to healthcare, they also harbor risks of disease transmission, air and water pollution, and social determinants of health like inadequate housing and social inequality. Simultaneously, migrants often face disproportionate health risks due to unstable living conditions, exploitation, and limited access to healthcare services.

Achieving the SDGs will necessitate comprehensive approaches that consider the intricate interplay of health and population dynamics. It means strengthening health systems, promoting universal health coverage, and addressing social determinants of health. It also implies crafting policies that recognize demographic realities and foster an environment conducive to sustainable development. Only by understanding and harnessing these dynamics can the world meaningfully progress towards realizing the SDGs, ensuring healthy lives and well-being for all.

Massive slums have become major features of cities in many low-income and middle-income countries. Here, in the first in a Series of two papers, we discuss why slums are unhealthy places with especially high risks of infection and injury. We show that children are especially vulnerable, and that the combination of malnutrition and recurrent diarrhoea leads to stunted growth and longer-term effects on cognitive development. We find that the scientific literature on slum health is underdeveloped in comparison to urban health, and poverty and health.
In the first paper in this Series we assessed theoretical and empirical evidence and concluded that the health of people living in slums is a function not only of poverty but of intimately shared physical and social environments. In this paper we extend the theory of so-called neighbourhood effects. Slums offer high returns on investment because beneficial effects are shared across many people in densely populated neighbourhoods. Neighbourhood effects also help explain how and why the benefits of interventions vary between slum and non-slum spaces and between slums.
Nanotechnology provides an emerging potent alternate mode of cancer therapy. Nanomaterials dispersion or solubility is of particular concern in utilising their full potential applications in biomedical fields. PEGylation of nanomaterials is considered to provide products with stealth properties, and physiological environment with no obvious adverse effects. The purpose of this work was to develop a sustainable one-step method for fabrication of hierarchical microspheres of PEGylated MoS 2 nanosheets using a stoichiometric ratio of Mo(VI) and thiourea.
Background China has achieved Millennium Development Goal 4 to reduce under-5 mortality rate by two-thirds between 1990 and 2015. In this study, we estimated the national and subnational levels and causes of child mortality in China annually from 1996 to 2015 to draw implications for achievement of the SDGs for China and other low-income and middle-income countries.
Background Hepatocellular carcinoma is a leading cause of cancer-related death in Africa, but there is still no comprehensive description of the current status of its epidemiology in Africa. We therefore initiated an African hepatocellular carcinoma consortium aiming to describe the clinical presentation, management, and outcomes of patients with hepatocellular carcinoma in Africa.
Effective communication to citizens is of prime importance during public health crises involving water. This paper takes a sequential mixed method approach to the problem of communicating drinking water risks prevention of exposure to health risks in cities.
In February, 2016, WHO released a report for the development of national action plans to address the threat of antibiotic resistance, the catastrophic consequences of inaction, and the need for antibiotic stewardship. Antibiotic stewardship combined with infection prevention comprises a collaborative, multidisciplinary approach to optimise use of antibiotics. Efforts to mitigate overuse will be unsustainable without learning and coordinating activities globally.
Anti-infective drugs have had a key role in the contemporary world, contributing to dramatically decrease mortality rates caused by infectious diseases worldwide. Antimicrobial peptides (AMPs) are multifunctional effectors of the innate immune system of mucosal surfaces and present antimicrobial activity against a range of pathogenic viruses, bacteria, and fungi. However, the discovery and development of new antibacterial drugs is a crucial step to overcome the great challenge posed by the emergence of antibiotic resistance.

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