Tay–Sachs disease is an inherited lysosomal storage disease resulting from mutations in the lysosomal enzyme, β-hexosaminidase A, and leads to excessive accumulation of GM2 ganglioside.
Sideroblastic anemia (SA) is characterized by bone marrow ring sideoblasts (RSs). RS reflect abnormal iron accumulation in the mitochondria of erythroblasts. Congenital SA is caused by the mutation of genes involved in iron-heme metabolism. The most frequent form of congenital SA is X-linked SA due to ALAS2 gene mutation.
This Article supports SDG 3 by analysing data from four international cohorts of patients with pulmonary arterial hypertension, a disease caused by rare genetic variants.
Elsevier,
Global Mental Health and Psychotherapy, Adapting Psychotherapy for Low- and Middle-Income Countries, Global Mental Health in Practice, 2019, Pages 87-126
This chapter addresses Goal 3 by exploring the use of cognitive behavioral therapy to treat mental health needs in low and middle income countries.
It has been estimated that European customers visit community pharmacies to access essential primary healthcare around 46 million times every day.
