Acquired immunodeficiency syndrome (AIDS) is a disease arising from human immunodeficiency virus (HIV). Antiretroviral therapy (ART) is a main therapeutic regimen for inhibiting HIV proliferation and viability. Identification of differentially expressed genes (DEGs) in HIV-infected patients with and without ART could provide theoretical evidence for deep research into the efficacy of ART and corresponding mechanism. 
Figure 4. A systems biology view of the aged breast microenvironment
This Review supports SDGs 3 and 5, focusing on screening, detection, and treatment of oestrogen receptor-positive breast cancers in older women, particularly in relation to recent moves to de-escalate some interventions for this population.
This Article supports SDGs 3 and 5, focusing on blood pressure and hypertension treatment and their association with cognitive impairment and dementia in older women.
A tissue biopsy to measure the role of mitochondria in the pathophysiology, is often not available. This article reviews biomarkers of mitochondrial dysfunction that can be measured in blood or blood cells suggests to use a panel of diverse blood biomarkers to identify a role of mitochondrial dysfunction.
Statistics related to the epidemiology of RDs and the importance of early diagnosis.
This article ties to SDG 3. This clinical review article, published in PET Clinics, looks at the effect of artificial intelligence on medical imaging for rare diseases. Key point: There is a significant need to recognize the challenge of data imbalance in rare diseases and to make concerted efforts to provide technical recommendations and guidelines.
This Article supports SDG 3 by estimating the prevalence of genetically confirmed facioscapulohumeral muscular dystrophy type 1, a rare disease, in China, showing that the estimated prevalence was 0.75 per million during 2001-2020.
This content links with Goal 3: Good health and well-being and Goal 10: Reduced Inequalities by showing how the issue of “inclusion” could be affected by the advancement of artificial intelligence (AI) in medicine through the interaction between rare diseases (RDs) and AI technology.
Elsevier,

Critical Care Rare Disease, Volume 17, Issue 1, January 2022, Pages 13-29

This content links with Goal 3: Good health and well-being and Goal 10: Reduced Inequalities by providing insights into diagnostic access for undiagnosed and rare diseases in critical care
This content links with Goal 3: Good health and well-being and Goal 10: Reduced Inequalities by providing information on the diagnosis and management of cardiovascular involvement in Fabry Disease.
This content aligns with Goal 3: Good Health as well as Goal 10: Reduced Inequalities by bringing to light research on HPV and breast cancer in women.

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