Global

This chapter explores the role of epigenetics in neurodevelopmental disabilities, highlighting how environmental factors influence gene expression and contribute to these conditions. It aligns with SDG 3 (Good Health and Well-being) by promoting understanding of mechanisms that can lead to improved treatments and health outcomes, and SDG 10 (Reduced Inequalities) by advocating equitable access to emerging epigenetic-based therapies and early interventions for affected individuals.

This chapter supports UN SDGs 7 (Affordable and Clean Energy), 9 (Industry, Innovation, and Infrastructure), 11 (Sustainable Cities and Communities), 13 (Climate Action), and 17 (Partnerships for the Goals) by promoting the transition to renewable energy sources, reducing greenhouse gas emissions, enhancing energy efficiency, fostering technological innovation, and emphasizing collaboration and innovation to drive the development of cleaner and more efficient energy solutions for a sustainable future.

This Viewpoint supports SDG 3 by highlighting the pervasive issues within health systems rooted in ableism and proposes an agenda to tackle ableism, aiming to make health systems responsive to the needs of people with disabilities.

This study investigates the therapeutic potential of nervonic acid (NA) in alleviating stroke-induced brain damage and post-stroke depression behaviors in rats, revealing that NA can improve neurological recovery, reduce infarct volume, and enhance depressive-like behaviors by modulating gut microbiota and metabolite activity. The findings suggest that NA could be a promising treatment option for stroke and associated post-stroke depression.