Research into coatings made from whey protein isolate and xanthan gum which could increase the shelf life of fruit and thus have potential to minimize post-harvest losses and food waste, supporting SDG2: Zero Hunger.
This chapter supports SDGs 3 and 16 by outlining key research needs, while emphasizing that reducing the burden of pulmonary, critical care and sleep disorders in migrants and refugees.
Niemann-Pick type C (NPC) disease, a lysosomal storage disorder caused by defective NPC1/NPC2 function, results in the accumulation of cholesterol and glycosphingolipids in lysosomes of affected organs, such as liver and brain. Moreover, increase of mitochondrial cholesterol (mchol) content and impaired mitochondrial function and GSH depletion contribute to NPC disease. However, the underlying mechanism of mchol accumulation in NPC disease remains unknown. As STARD1 is crucial in intramitochondrial cholesterol trafficking and acid ceramidase (ACDase) has been shown to regulate STARD1, we explored the functional relationship between ACDase and STARD1 in NPC disease.
This Research Paper supports SDG 5 by providing an evidence base on organisational interventions for advancing women in leadership across diverse settings, with lessons for the health-care sector.
This chapter aligns with Goal 3: Good Health and Wellbeing and Goal 14: Life under Water by discussing the ethical considerations and welfare needs of zebrafish in laboratory settings.
There is an urgent need to endorse a protective therapy for ALS patients. Possible treatments might be based on the underlying molecular pathophysiology. Some of the ALS dysregulated routes could be targeted by a single hit in NRF2. NRF2 emerged as a druggable target in preclinical and clinical trials for ALS.
World Alzheimer's Day is an international campaign organised by Alzheimer's Disease International to raise awareness and highlight issues faced by people affected by dementia. It takes place every year on September 21st and is the focus of World Alzheimer's Month. In support of this year’s theme – ‘Know dementia, know Alzheimer's’ - Elsevier presents a curated, open access collection of over 70 journal articles and book chapters focused on shining a light on the warning signs of dementia and the importance of a timely diagnosis.
Given their carbon emissions, pharmaceutical companies must intensify their efforts and play an active role in addressing climate change.
This study demonstrates that systems science provides positive implementation approaches to design and translates nutrition behaviors and knowledge into practice.
This exploratory study examines parental opinions about receiving climate change information at their child's checkup.
