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Clinical assessment of speech abnormalities in Cerebellar Ataxia (CA) is subjective and prone to intra- and inter-clinician inconsistencies. This paper presents an automated objective method based on a single syllable repetition task to detect and quantify speech-timing anomalies in ataxic speech. Such a technique is non-invasive, reliable, fast, cost-effective and can be used in the comfort of home without any professional assistance.
Elsevier, International Journal of Radiation Oncology Biology Physics, Volume 106, 15 March 2020
In the face of the growing challenges brought about by human activities, effective planning and decision-making in biodiversity and ecosystem conservation, restoration, and sustainable development are urgently needed. Ecological models can play a key role in supporting this need and helping to safeguard the natural assets that underpin human wellbeing and support life on land and below water (United Nations Sustainable Development Goals; SDG 15 & 14).
Elsevier, Journal for Nurse Practitioners, Volume 16, March 2020
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and a leading cause of dementia in the elderly. AD initially presents as mild cognitive impairment (MCI); later, as AD progresses, memory and cognition are destroyed, preventing the ability to carry out activities of daily living. The primary care provider may be the first to suspect MCI, and screening tests can help with diagnosis. Development of drugs for cognitive decline in AD has been slow; however new therapies are in the pipeline and discovery of biomarkers make early diagnosis and future treatment of AD hopeful.
Glucose-dependent Insulinotropic polypeptide (GIP) is a peptide hormone of the incretin family. It has growth factor properties and can re-activate energy utilization. In progressive neurodegenerative disorders such as Alzheimer's and Parkinson's disease, energy utilization is much reduced, and GIP has the potential to reverse this. Furthermore, GIP can reduce the inflammation response in the brain and reduce levels of pro-inflammatory cytokines. Tests in animal models of Alzheimer's and Parkinson's disease show good neuroprotective effects.
In the last decade, the consumption trend of organic food has increased dramatically worldwide. Since only a few pesticides are authorized in organic crops, concentrations are expected to range at zero or ultra-trace levels. In this context, the aim of the present study was to investigate the need for an improvement in the residue controls at very low concentrations (
Persuading individuals to engage in pro-environmental behavior is challenging. Interactive media, such as virtual environments and video games, present opportunities to minimize psychological distance and bolster perceived risks associated with environmental threats. In this experiment, we tested the effects of a serious game that allowed users to engage in environmental cleanup. In the virtual environment, participants (N = 190) navigated down a polluted river that was described as geographically and temporally close or distant.

A grand challenge facing humanity is how to produce food for a growing population in the face of a changing climate and environmental degradation. Although empirical evidence remains sparse, management strategies that increase environmental sustainability, such as increasing agroecosystem diversity through crop rotations, may also increase resilience to weather extremes without sacrificing yields.

Elsevier,

Renewable and Sustainable Energy Reviews, Volume 120, March 2020

Smart home technologies refer to devices that provide some degree of digitally connected, automated, or enhanced services to building occupants. Smart homes have become central in recent technology and policy discussions about energy efficiency, climate change, and the sustainability of buildings. Nevertheless, do they truly promote sustainability goals? In addition, what sorts of benefits, risks, and policies do they entail?

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