Elsevier,
Revista Espanola de Geriatria y Gerontologia, Volume 59, 1 January 2024
The objective of this study was to assess the neuropsychological characteristics of individuals with early-onset Alzheimer's disease (EOAD), late-onset Alzheimer's disease (LOAD), and very-late-onset Alzheimer's disease (VLOAD). The findings indicate notable neuropsychological variations across different age groups, demonstrating a progressive decline in cognitive function with age rather than distinct clinical presentations.
Elsevier,
Journal of Water Process Engineering, Volume 57, January 2024
Pakistan's water resources experiencing mounting pressure. UN SDG 6 provides a roadmap for achieving sustainable water management. Long-term planning and community engagement are key to success. Policy recommendations include efficient pricing and climate change integration.
Elsevier,
Neurobiology of Disease, Volume 190, January 2024
In Alzheimer's disease research, cerebrospinal fluid (CSF) biomarkers Amyloid beta (Aβ), Tau, and pTau are well-validated, and this study demonstrates that a Z-score based harmonization approach can effectively standardize CSF and amyloid imaging data across multiple cohorts, providing consistent biomarker cut-offs and comparable GWAS results to traditional methods, without introducing spurious findings.
Elsevier,
Journal of Process Control, Volume 133, January 2024
The authors put forward a mathematical model for examining the impact of water, sanitation and hygiene (WASH) services on reducing the transmission of waterborne diseases such as enteric diarrheal disease (EDD). It is found that wastewater and sewage treatment (WST) control has the most significant impact in terms of WASH interventions employed. The findings have could have very important public health potential and tie in strongly with the goals of SDG 6.
Elsevier,
Journal of Virological Methods, Volume 323, January 2024, 114852
This article supports SDG 3 as understanding the role of HCV core proteins in viral diseases is crucial to elucidating disease mechanisms and identifying potential drug targets. However, purification challenges may hinder the comprehensive elucidation of the structure and biochemical properties of HCV core proteins.
Elsevier,
Behavioural Brain Research, Volume 456, 5 January 2024
This article discusses the manifestation of apathy-like behaviors in Alzheimer's disease (AD) and frontotemporal dementia (FTD) mouse models through the assessment of nest-building behavior, highlighting differences in nesting proficiency and anhedonia between tau transgenic mice lines, suggesting apathy-like phenotypes in the context of neurodegenerative diseases.
Elsevier,
The Lancet Planetary Health, Volume 8, January 2024
This study supports SDGs 3, 6, and 14 by highlighting the importance of freshwater biodiversity for human and planetary health, and suggesting that local and regional efforts for monitoring and improving ecosystem health are essential for reversing the current crisis in this area.