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This study demonstrated that physical exercise pretreatment improves recognition memory and enhances structural synaptic plasticity in the hippocampus of Alzheimer’s disease (AD) rats, primarily through the activation of hippocampal TREM2. Blocking TREM2 diminished these neuroprotective effects, indicating that exercise mitigates synaptic injury and cognitive decline in AD via a TREM2-dependent mechanism.
This study identifies two CSF proteomic panels that accurately stage Alzheimer’s pathology, outperform current biomarkers, and predict dementia progression over 10 years, enhancing diagnosis and clinical trial stratification.
Big data shows significant potential for deep decarbonization in the transportation sector, while advances in artificial intelligence (AI) technologies help extracting valuable knowledge from such data. This study reviews the applications of big data and AI technologies in transportation, encompassing data accumulation, pattern understanding, and uncovering the intricate nexus between transportation activities and carbon emissions, ultimately providing insights for achieving carbon neutrality.

This article proposed a new research framework to help better account for the broader sustainability (e.g. local community well-being, affordability, accessibility) in the net-zero energy transition

Supported by Dubai Cares and together with Unbounded Associates and Plan International, the Ban Ki-moon Centre presents the “Your Future in Green Jobs” Online Course and Mentorship. Designed for people of 14-20 years old, this course aims to empower youth to connect their passion, interests, and skills with meaningful careers that address climate change head-on.

The program has two key components:

Engaging in philanthropic activities is being pursued by many well-established supply chains. Donations are a form of charitable activities that not only promote the social responsibility of a corporation but also enhance its public image, which in turn creates more benefits for the supply chain. Prosocial preferences of customers are considered the primary drivers that persuade supply chains to donate. In this chapter, various donation programs within supply chains are introduced, and the challenges associated with them are briefly discussed.

Image of world map with SDG icons and people.  Title of RELX SDG Inspiration Day 2025 - Future of Philanthropy: Stepping up for the UN Sustainable Development Goals

RELX SDG Inspiration Day 2025

The Future of Philanthropy: Stepping up for the United Nations Sustainable Development Goals

Can philanthropy bridge the funding gap necessary to advance the Sustainable Development Goals?

Join thought leaders, including Ban Ki-moon, 8th United Nations Secretary General, in discussing the role for philanthropy in addressing the United Nations Sustainable Development Goals (SDGs).

Elsevier,

Trends in Ecology & Evolution, Volume 40, Issue 4, April 2025, Pages 315-319

Foraging wild plants and mushrooms can be both beneficial and detrimental to biodiversity. We examine the role of stewardship practices, which are grounded in care, knowledge, and agency, in fostering sustainable use of wild species. These practices are pervasive among foragers across social–ecological systems yet neglected in research and policymaking.

This study reviews the growth and current state of the specialty of emergency medicine (EM) around the world. The 2023 World Health Assembly resolution emphasized emergency care as a cost-effective means to reduce health disparities and called for increased investment in emergency and critical care. Although EM is an increasingly recognized medical specialty, its growth faces barriers such as insufficient training programs, workforce shortages, and systemic challenges including resource shortages and burnout.

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