South America

Neurobiology of Brain Disorders (Second Edition), Biological Basis of Neurological and Psychiatric Disorders, 2022, Pages 313-336

This book chapter advances SDG #3 and #10 by reviewing several key topics that influence our understanding of pathogenic mechanisms and lead to the identification of novel therapeutic strategies. These include the diagnostic spectrum of MCI and AD, genetic risk alleles associated with late-onset AD, structures of gamma-secretase and tau, imaging and fluid biomarkers, the role of microglia and neuroinflammation, and novel animal models of AD.
An Article on the vulnerability of Indigenous populations to pandemics, in the context of SDGs 3 and 10, focusing specifically on the clinical characteristics and outcomes following COVID-19 in Indigenous Brazilian individuals.
Background: Hepatitis C is a preventable and treatable disease that has been declared a public health problem. In 2012, the prevalence of HCV serum anti-bodies in the Mexican adult population aged 20 to 49 years was 0·30%. Methods: We randomly selected a probabilistic sub-sample of 12,389 adults (20+ years) from adults participating in the National Health and Nutrition Survey (ENSANUT) 2018 who provided a venous blood sample. Anti-HCV antibodies and HCV RNA were determined for this sub-sample.
An analysis of ethnic inequalities in reproductive, maternal, newborn and child health interventions in Ecuador, in the context of SDG 3 and 10, showing that Indigenous people are most likely to face difficulty accessing such services.
This book chapter advances SDG #3 and #10 by presenting drug delivery systems based on nanotechnology to treat Alzheimer’s disease.
This book chapter advances SDG #3 and #10 by highlighting a few newly updated nano drug delivery technologies implemented in Alzheimer’s disease therapies and prospects for the future regarding potential molecular mechanisms of nano drug delivery methods
This study supports SDG 3 and 13 by quantifying the risk and attributable burden of hospitalisations for renal diseases related to ambient temperature, showing that this risk was positively associated with daily mean temperature and was more prominent in women, children aged 0–4 years, and older people aged ≥80 years. The findings highlight the need for the development of more policies to prevent heat-related hospitalisations and to mitigate climate change.

The Lancet Regional Health - Americas, Volume 10, 2022, 100222

This study supports SDG 3 and 10 by discussing possible determinants of the impact of the COVID-19 pandemic on the Brazilian health system through the lenses of health system resilience and geographical inequalities. The findings show that lack of proper planning to improve resilience resulted in the decrease of a quarter of the amount of health-care procedures, increasing already existing health disparities in the country and highlighting the need to allocate resources in socioeconomically vulnerable regions to reduce avoidable deaths.
This study supports SDG 3 by investigating the association between increasing the quality of primary health care in Brazil, with highly-skilled health professionals and integrated community health workers, and reductions in hospitalisations and mortality. These findings suggest that high quality, multidisciplinary primary health care remains essential to strengthening health systems in both high-income countries and in low-income and middle-income countries.
This study supports SDG 3 and 10 by analysing the association between income inequality and more than 60 outcomes of non-communicable diseases in Brazil. These findings emphasise the importance of addressing wider social determinants of health and the synergistic benefits of tackling inequalities.