Health and population

Health and population dynamics are intertwined, embodying an intricate relationship with significant implications on the Sustainable Development Goals (SDGs). Health is fundamentally at the center of these 17 global goals, aimed to transform the world by 2030. Specifically, Goal 3 endeavors to "Ensure healthy lives and promote well-being for all at all ages." It acknowledges that health is pivotal to human life quality, social cohesion, and sustainable development. Inextricably linked to this are the complexities of population dynamics, including growth rates, age structure, fertility and mortality rates, and migration patterns.

With the world's population projected to exceed 9.7 billion by 2050, the pressure on health systems will undoubtedly escalate. The demographic transition, with an aging population and an increasing prevalence of non-communicable diseases, poses new challenges for health systems globally. Additionally, areas with high fertility rates often overlap with extreme poverty, resulting in heightened health risks, including higher maternal and child mortality rates, malnutrition, and infectious diseases.

Moreover, rapid urbanization and migration present both opportunities and threats to health. While urban areas may provide better access to healthcare, they also harbor risks of disease transmission, air and water pollution, and social determinants of health like inadequate housing and social inequality. Simultaneously, migrants often face disproportionate health risks due to unstable living conditions, exploitation, and limited access to healthcare services.

Achieving the SDGs will necessitate comprehensive approaches that consider the intricate interplay of health and population dynamics. It means strengthening health systems, promoting universal health coverage, and addressing social determinants of health. It also implies crafting policies that recognize demographic realities and foster an environment conducive to sustainable development. Only by understanding and harnessing these dynamics can the world meaningfully progress towards realizing the SDGs, ensuring healthy lives and well-being for all.

Elsevier,

Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume 1 - Biology and Pathophysiology, 2022, Pages 257-285

This chapter aligns with the SDG goal 3 of good health and wellbeing by showing the current view of the pathogenesis of HBV and HCV along with the report on their relation to the genotypes.
Background: China has the highest prevalence of hepatitis B virus (HBV) infection worldwide. Universal HBV screening might enable China to reach the WHO 2030 target of 90% diagnostics, 80% treatment, and 65% HBV-related death reduction, and eventually elimination of viral hepatitis. We evaluated the cost-effectiveness of implementing universal HBV screening in China and identified optimal screening strategies.
Map of study areas with changes in annual mean of PM2·5 from 2014 to 2017

Background: Air pollution might accelerate cognitive ageing; it is unclear whether large-scale interventions, such as China's Clean Air Act (CCAA), can mitigate cognitive deterioration. We aimed to evaluate the effect of CCAA on changes in cognitive function in older adults. Methods: In this population-based, quasi-experimental study, we did a difference-in-differences analysis of the data collected during the 2014 and 2018 waves of the Chinese Longitudinal Healthy Longevity Survey (CLHLS).

Elsevier,

Microneedles, 2022, Pages 115-138

The sampling of interstitial fluid for real-time assay requires techniques that are sensitive, rapid, painless, minimally invasive and easy to use by patients. Microneedles can be incorporated into biosensors with subsequent use of these platforms for continuous monitoring or bio-chemical detection of analytes in the dermal interstitial fluid. Supports the goal of SDG 3.8 to achieve universal health coverage, including financial risk protection, access to quality essential health-care services and access to safe, effective, quality and affordable essential medicines and vaccines for all.
Elsevier,

eBioMedicine, Volume 76, February 2022

This Review supports SDG 3 and 10 by highlighting how genomics research intersects with existing racial and ethnic inequalities and forms of exclusion; there is no universally accepted, consistently applied method for categorising genomic data, which the authors argue is problematic, both from a clinical and scientific perspective, but more fundamentally in terms of the ability of genomics research to achieve the core ethical values of equity and justice.
This Article supports SDGs 3 and 5, focusing on the association between testosterone concentrations and risk of major adverse cardiac events in older women.
Elsevier,

Diabetes Without Needles, Non-invasive Diagnostics and Health Management, 2022, Pages 27-92

Introduces diabetes including past, present, and future achievements in this field. The goal of SDG target 3.4.1 is to reduce the mortality rate attributed to cardiovascular disease, cancer, diabetes or chronic respiratory disease
Percentage change between 2019 and 2050 in all-age number of individuals with dementia by country.
An article on the global prevalence of dementia, in the context of SGD 3, focusing specifically on forecasting country-level estimates of dementia prevalence attributable to high BMI, high fasting glucose, and smoking, from 2019 to 2050.
This book chapter advances SDG #3 and #10 by reviewing studies that showed treatments with multiple sessions of rTMS can influence cognition in people with neurodegenerative diseases. The chapter also considers novel therapeutic approaches based on the clinical use of rTMS.
This book chapter advances SDG 3 and 10 by presenting that (1) some of these depression scales do not correlate, suggesting that they assess different aspects of depression; (2) reports of depression in dementia vary based on depression in dementia scale used; and (3) severe memory impairment may impact the ability to assess depression in the patients using self-reports.

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