This review examines the role of the autonomic nervous system in controlling cerebral blood flow (CBF) in dementia, highlighting that while cerebral autoregulation remains largely intact, the loss of neurovascular coupling may drive cognitive dysfunction, and exploring clinical and animal studies to identify potential biomarkers and therapeutic targets.
This Article supports SDG 3 by using a novel individual-based mathematical model to describe HIV transmission dynamics in heterosexual sex work networks in the Middle East and north Africa to estimate HIV incidence and the potential impact of interventions among female sex workers, clients, and client spouses.
This longitudinal study looks at the aging characteristics of those infected with HIV, and suggests a role for HIV in the earlier onset of clinical aging.
This Article supports SDG 3, 4, and 5 by highlighting that more than 160 million women aged 15-24 years globally have a need for contraception that is not currently met by existing family planning programs, thus hindering or eliminating their education and employment opportunities.
The way how the emergence of mitochondria research field improved our knowledge on the hmajor metabolic pathways. How mitochondria 3-D architecture fits with different cellular and physiological functions. Putative interlink between mitochondrial dysfunction and neurodegeneration – the cases of AD and PD. Strategies to develop a mitochondria-targeted therapy for neurodegenerative diseases.
Hepatitis C has increased in women of childbearing age and has important implications in women who become pregnant and their infants. The effect that hepatitis C has on pregnancy outcomes was evaluated as well as the rate of hepatitis C transmission to infants in a large database with linked mother-infant records. It was found that active hepatitis C during pregnancy increased the risk of pregnancy complications. Also identified were very low rates of testing of infants born to mothers with hepatitis C but found higher rates of hepatitis C transmission to infants in mothers with higher virus levels.
An Article on the global prevalence, mortality, and disability-adjusted life-years of hepatitis B, in the context of SDG 3, focusing specifically on a comparison of estimates to WHO elimination targets.
The emergence of monkeypox as a zoonotic disease and its potential spread among specific communities raises concerns for public health. The link between monkeypox and viral hepatitis, including the risk of coinfection and impact on liver function, is an important area of research for combating hepatitis.
The Lancet Healthy Longevity, Volume 3, Issue 7, July 2022, Pages e501-e512
This Personal View supports Sustainable Development Goal 3 by summarising the limitations of existing research into the role of nutritional factors in dementia, and propose recommendations to guide future trial developments.
An Article on the burden of chronic hepatitis B and C infections in Japan, in the context of SDG 3, highlighting the need for improved screening strategies for hepatitis C virus and development of new therapies leading to a functional cure for hepatitis B virus.
