This book chapter advances SDG3 Good Health and Wellbeing and SDG10 Reducing Inequalities by exploring a fall-detection monitoring solution that implements both accelerometer and sound-based detection algorithm.
How physical activity improves mental health.
Coenzyme Q10 (CoQ10) deficiency syndrome is a rare disease included in the family of mitochondrial diseases, which is a heterogeneous group of genetic disorders characterized by defective energy production. CoQ10 biosynthesis in humans requires at least 11 gene products acting in a multiprotein complex within mitochondria. The high-throughput screening (HTS) method based on the stabilization of the CoQ biosynthesis complex (Q-synthome) produced by the COQ8 gene overexpression is proven here to be a successful method for identifying new molecules from natural extracts that are able to bypass the CoQ6 deficiency in yeast mutant cells. The main features of the new approach are the combination of two yeast targets defective in genes with different functions on CoQ6 biosynthesis to secure the versatility of the molecule identified, the use of glycerol as a nonfermentable carbon source providing a wide growth window, and the stringent conditions required to mark an extract as positive. The application of this pilot approach to a representative subset of 1200 samples of the Library of Natural Products of Fundación MEDINA resulted in the finding of nine positive extracts. The fractionation of three of the nine extracts allowed the identification of five molecules; two of them are present in molecule databases of natural extracts and three are nondescribed molecules. The use of this screening method opens the possibility of discovering molecules with CoQ10-bypassing action useful as therapeutic agents to fight against mitochondrial diseases in human patients.
Elsevier,
Adolescent Addiction (Second Edition), Epidemiology, Assessment, and Treatment, Practical Resources for the Mental Health Professional, 2020, Pages 215-240
This chapter addresses Goal 3 by discussing smartphone addiction in adolescents.
This chapter supports SDGs 3 and 16 by describing disaster management in the international context and introduces the community of international disaster management stakeholders (which includes governmental agencies, international organizations, nongovernmental organizations, and financial institutions) that support the preparedness for, mitigation of, response to, and recovery from disaster events.
This book chapter addresses goals 14, 15, 6 and 11 by looking at the affects of pollutants on the biosphere.
Furthering SDGs 5 and 10, this report aims to better understand the role gender plays in the global research enterprise and inspire evidence-based policy driven by powerful data. It examines research participation, career progression and perceptions across the European Union and 15 countries globally in 26 subject areas. The report concludes that while the participation of women in research is increasing overall, inequality remains across geographies and subject areas in terms of publication outputs, citations, awarded grants and collaborations.
Background: Pregnancy is characterized with several physical and mental changes in women. These changes cause mental health problems in pregnant women and especially in nulliparous women. Objective: To determine the effects of cognitive-behavioral counseling on mental health of pregnant women. Method: The study was carried out as a quality of life clinical trial with a control group. The participants were 60 pregnant women (less than 20 weeks) who visited Kamyaran-based health centers (Iran) in 2018. The participants were allocated randomly to experiment and control groups (n = 30 each).
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Global Citizen, 28th February 2020
Advancing SDGs 4 and 5, this article discusses how stereotypical assumptions about boys’ reading skills affect students’ reading outcomes.
Environmentalism and sustainability are two buzzwords that have come to represent an awakening of the people's collective conscience over the last two decades or so. Pedantically, the two words have slightly different meanings, yet there is sufficient overlap that they are commonly used interchangeably.
