Global

Global issues are inextricably linked to the United Nations' Sustainable Development Goals (SDGs). Established in 2015, the SDGs provide a universal blueprint for peace and prosperity for people and the planet, now and into the future. They encompass a wide array of global challenges, such as poverty, inequality, climate change, environmental degradation, peace and justice, among others, making them a comprehensive framework for international cooperation and action. Each SDG is further divided into specific targets, which are designed to address these challenges at multiple levels.

One of the fundamental principles of the SDGs is that they are interconnected; solving one issue often contributes to resolving others. For example, tackling poverty (SDG 1) can help reduce hunger (SDG 2) and improve health and well-being (SDG 3). Similarly, pursuing quality education (SDG 4) can empower women (SDG 5), and create decent work and economic growth (SDG 8). In turn, these efforts can contribute to reduced inequalities (SDG 10) and promote peace, justice and strong institutions (SDG 16).

In the era of globalization, the role of international cooperation in achieving the SDGs is crucial. The global nature of many contemporary challenges, such as climate change or the COVID-19 pandemic, necessitates that nations work together to address these issues. As such, the SDGs provide a shared global agenda that transcends national borders and brings together diverse stakeholders, including governments, civil society, the private sector, and individuals.

While the SDGs provide the framework for global action, they also have implications for local and national contexts. Countries, regions, and cities are encouraged to tailor the global SDGs to their own contexts, developing local strategies and initiatives to achieve these goals. By addressing global issues at both global and local scales, the SDGs promote a multilevel, integrated approach to sustainable development.

Overall, the relationship between global issues and the SDGs is one of mutual influence and interdependence. The SDGs reflect the urgent need to address global challenges, while also providing a pathway towards solutions. They are a testament to the power of international cooperation and the potential for collective action to create a more sustainable, equitable, and prosperous world.

SDG 6: Clean Water and Sanitation graphic showing key metrics for research into clean water and sanitation
The latest analysis of SDG-supporting research focusses on SDG 6: Clean Water and Sanitation. This graphic shows key metrics for research into clean water and sanitation.
Traumatic brain injury (TBI) is one the most common human afflictions, contributing to long-term disability in survivors. Emerging data indicate that functional improvement or deterioration can occur years after TBI. In this regard, TBI is recognized as risk factor for late-life neurodegenerative disorders. TBI encompasses a heterogeneous disease process in which diverse injury subtypes and multiple molecular mechanisms overlap.
Rationale: Transgender people face unique challenges, such as structural, interpersonal, and individual vulnerabilities to chronic diseases. Stigma and prejudice may hamper their access to health care and prevent their inclusion in the labor market, as well as cause exposition to violence. Labor market exclusion contributes to engagement in survival sex work, which increases HIV infection vulnerability.
Background: Memory for music has attracted much recent interest in Alzheimer's disease but the underlying brain mechanisms have not been defined in patients directly. Here we addressed this issue in an Alzheimer's disease cohort using activation fMRI of two core musical memory systems. Methods: We studied 34 patients with younger onset Alzheimer's disease led either by episodic memory decline (typical Alzheimer's disease)or by visuospatial impairment (posterior cortical atrophy)in relation to 19 age-matched healthy individuals.
This chapter addresses SDGs 3 and 10 by exploring the process of Disability-inclusive Disaster Risk Reduction (DiDRR) from two Deaf Disaster Risk Reduction (DRR) practitioners working in partnership with an international team.
Alzheimer's disease (AD) is considered a polygenic disorder. This view is clouded, however, by lingering uncertainty over how to treat the quasi “monogenic” role of apolipoprotein E (APOE). The APOE4 allele is not only the strongest genetic risk factor for AD, it also affects risk for cardiovascular disease, stroke, and other neurodegenerative disorders. This review, based mostly on data from human studies, ranges across a variety of APOE-related pathologies, touching on evolutionary genetics and risk mitigation by ethnicity and sex.
Elsevier, The Lancet, Volume 393, 9 - 15 February 2019
The purpose of this Review is to provide evidence for why gender equality in science, medicine, and global health matters for health and health-related outcomes. We present a high-level synthesis of global gender data, summarise progress towards gender equality in science, medicine, and global health, review the evidence for why gender equality in these fields matters in terms of health and social outcomes, and reflect on strategies to promote change.

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