Elsevier,
Neuropharmacology, Volume 259, 15 November 2024
This review explores using nanotechnology to enhance the delivery of neuroprotective phytochemicals from medicinal plants for Alzheimer's disease (AD), addressing issues of bioavailability, solubility, and blood-brain barrier penetration, and highlights the potential of nanocarriers to revolutionize neuroprotective drug delivery and improve patient outcomes.
Elsevier,
Brain Research, Volume 1843, 15 November 2024
This study developed a novel mouse model with tamoxifen-inducible knockout of the Gnpat gene, enabling late-onset plasmalogen deficiency to investigate its role in Alzheimer's disease. The model exhibited significant plasmalogen reduction and associated behavioral and nerve function changes, providing a valuable tool for future research on plasmalogen involvement in neurodegeneration and potential therapies.
Elsevier,
Journal of Ethnopharmacology, Volume 333, 28 October 2024
This review investigates the connection between Type 2 Diabetes Mellitus and Alzheimer's disease, focusing on common mechanisms and the potential of traditional Indian herbs to manage both conditions. It also addresses the challenges and innovative strategies in delivering herbal formulations.