Articles

Elsevier,

Brain Research, Volume 1843, 15 November 2024

This study developed a novel mouse model with tamoxifen-inducible knockout of the Gnpat gene, enabling late-onset plasmalogen deficiency to investigate its role in Alzheimer's disease. The model exhibited significant plasmalogen reduction and associated behavioral and nerve function changes, providing a valuable tool for future research on plasmalogen involvement in neurodegeneration and potential therapies.
Elsevier,

Neuropharmacology, Volume 259, 15 November 2024

This review explores using nanotechnology to enhance the delivery of neuroprotective phytochemicals from medicinal plants for Alzheimer's disease (AD), addressing issues of bioavailability, solubility, and blood-brain barrier penetration, and highlights the potential of nanocarriers to revolutionize neuroprotective drug delivery and improve patient outcomes.
Elsevier,

Pharmacological Research, Volume 208, October 2024

The study explores the use of a novel gene delivery system, AAV-aMTD-Parkin, to enhance motor and cognitive functions in animal models of Parkinson’s and Alzheimer’s diseases. This system improves the delivery efficiency of therapeutic proteins, potentially offering a new treatment approach for these neurodegenerative disorders.
Elsevier,

Brain Research, Volume 1841, 15 October 2024

This study found that female 5XFAD mice exhibit early impairments in prefrontal-dependent cognitive functions and increased activity of prefrontal PV neurons, unlike their male counterparts. These findings suggest a potential mechanism for the higher risk of Alzheimer's disease in women, highlighting sex-specific early deregulation in the prefrontal cortex.
Elsevier,

Archaeological Research in Asia, Volume 39, September 2024

This research examines how indigenous archaeology and how the emergence of the first urban centers in the Mongolian steppe coincided with the establishment of the Uyghur Khaganate during the mid-eighth century CE.
Elsevier,

Brain Research, Volume 1838, 1 September 2024

The study demonstrates that the peptide PHDP5, which inhibits dynamin-MT interaction, can rescue impaired endocytosis and synaptic transmission caused by tau in presynaptic terminals. When administered intranasally to Alzheimer's disease (AD) model mice, PHDP5 significantly improved learning and memory, suggesting its potential as a candidate for human AD therapy.
Elsevier,

Journal of Neuroscience Methods, Volume 409, September 2024

Despite significant investment, effective treatments for Alzheimer's disease (AD) have been elusive, necessitating improved quality and reproducibility of foundational laboratory evidence; to address this, AD-SOLES, an integrated workflow of automated tools and a publicly accessible interactive dashboard, has been developed to collect, curate, and visualize in vivo experimental evidence, enhancing evidence synthesis, tracking reporting quality, and aiding researchers in locating relevant data.
Elsevier,

Pharmacological Research - Modern Chinese Medicine, Volume 12, September 2024

The study investigates the neuroprotective effects of hordenine against AlCl3-induced Alzheimer’s disease in rats. Results show that hordenine improves memory and cognitive functions, suggesting its potential to reverse oxidative stress and neuroinflammation associated with Alzheimer’s
Elsevier,

Australian and New Zealand Journal of Public Health, Volume 48, August 2024

This paper seeks to describe and categorise some of the most common behaviours and practices of public health professionals and institutions that introduce or sustain systematic ethnic bias into public health work and thus potentially perpetuate or exacerbate Indigenous inequities in health.
RELX

More than 1100 people came together virtually on 18 June 2024 for the tenth edition of the RELX SDG Inspiration Day: "In the Age of AI: Information to Advance the UN Sustainable Development Goals (SDGs)." The annual online event brings together thought leaders, corporate representatives, students, investors, governments, and NGOs to explore pressing issues, gain practical insight, and inspire action on the United Nations Sustainable Development Goals (SDGs).

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