Elsevier, Geography and Sustainability, Volume 1, March 2020
Water footprint (WF) measures human appropriation of water resources for consumptive use of surface and ground water (blue WF) and soil water (green WF) and for assimilating polluted water (grey WF). Questions have been often asked about the exact meaning behind the numbers from WF accounting. However, to date environmental sustainability of WF has never been assessed at the sub-national level over time. This study evaluated the environmental sustainability of blue, green and grey WF for China's 31 mainland provinces in 2002, 2007 and 2012, and identified the unsustainable hotspots.
Elsevier, Journal for Nurse Practitioners, Volume 16, March 2020
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and a leading cause of dementia in the elderly. AD initially presents as mild cognitive impairment (MCI); later, as AD progresses, memory and cognition are destroyed, preventing the ability to carry out activities of daily living. The primary care provider may be the first to suspect MCI, and screening tests can help with diagnosis. Development of drugs for cognitive decline in AD has been slow; however new therapies are in the pipeline and discovery of biomarkers make early diagnosis and future treatment of AD hopeful.
Elsevier, Peptides, Volume 125, March 2020
Glucose-dependent Insulinotropic polypeptide (GIP) is a peptide hormone of the incretin family. It has growth factor properties and can re-activate energy utilization. In progressive neurodegenerative disorders such as Alzheimer's and Parkinson's disease, energy utilization is much reduced, and GIP has the potential to reverse this. Furthermore, GIP can reduce the inflammation response in the brain and reduce levels of pro-inflammatory cytokines. Tests in animal models of Alzheimer's and Parkinson's disease show good neuroprotective effects.
Elsevier, Food Chemistry: X, Volume 5, 30 March 2020
In the last decade, the consumption trend of organic food has increased dramatically worldwide. Since only a few pesticides are authorized in organic crops, concentrations are expected to range at zero or ultra-trace levels. In this context, the aim of the present study was to investigate the need for an improvement in the residue controls at very low concentrations (
Elsevier, Telematics and Informatics, Volume 46, March 2020
Persuading individuals to engage in pro-environmental behavior is challenging. Interactive media, such as virtual environments and video games, present opportunities to minimize psychological distance and bolster perceived risks associated with environmental threats. In this experiment, we tested the effects of a serious game that allowed users to engage in environmental cleanup. In the virtual environment, participants (N = 190) navigated down a polluted river that was described as geographically and temporally close or distant.
Elsevier, Mitochondrion, Volume 51, March 2020
This paper is written for non-specialists in mitochondrial biology to provide access to an important area of science that has broad implications for all people. The cell danger response (CDR) is a universal response to environmental threat or injury. Once triggered, healing cannot be completed until the choreographed stages of the CDR are returned to an updated state of readiness. Although the CDR is a cellular response, it has the power to change human thought and behavior, child development, physical fitness and resilience, fertility, and the susceptibility of entire populations to disease.
The Lancet Global Health, Volume 8, March 2020
This study supports SDG 3 and 10 by analysing data from 415 ethnic groups in 36 low-income and middle-income countries, and showing substantial ethnic disparities in under-5 mortality across the countries studied. These findings are crucial for monitoring trends and examining the impact of health interventions on child survival across different ethnic groups.
Elsevier, The Lancet Global Health, Volume 8, March 2020
Background: The WHO elimination strategy for hepatitis C virus advocates scaling up screening and treatment to reduce global hepatitis C incidence by 80% by 2030, but little is known about how this reduction could be achieved and the costs of doing so. We aimed to evaluate the effects and cost of different strategies to scale up screening and treatment of hepatitis C in Pakistan and determine what is required to meet WHO elimination targets for incidence.