Articles

Despite significant investment, effective treatments for Alzheimer's disease (AD) have been elusive, necessitating improved quality and reproducibility of foundational laboratory evidence; to address this, AD-SOLES, an integrated workflow of automated tools and a publicly accessible interactive dashboard, has been developed to collect, curate, and visualize in vivo experimental evidence, enhancing evidence synthesis, tracking reporting quality, and aiding researchers in locating relevant data.

The study investigates the neuroprotective effects of hordenine against AlCl3-induced Alzheimer’s disease in rats. Results show that hordenine improves memory and cognitive functions, suggesting its potential to reverse oxidative stress and neuroinflammation associated with Alzheimer’s

This paper seeks to describe and categorise some of the most common behaviours and practices of public health professionals and institutions that introduce or sustain systematic ethnic bias into public health work and thus potentially perpetuate or exacerbate Indigenous inequities in health.

This study evaluated the behavioral, physiological, and molecular effects of social isolation (SI) in adult zebrafish, and whether the animals recover such changes after their reintroduction to the social environment. The results show that SI altered social behaviors, neural activity, and serotonergic and dopaminergic signaling in zebrafish, but these changes were reversed after the animals were reintroduced to a social context for 6 days.