Elsevier,
The Lancet Microbe, Volume 4, August 2023
This Article supports SDG 3 by showing that international transmission of hepatitis C virus has occurred in recent years among men who have sex with men. This suggests that international coordination will be needed for microelimination in this population.
Elsevier,
eClinicalMedicine, Volume 62, August 2023
Population-based surveys are expensive and time consuming. By determining state-level seropositivity using national testing service data and a Bayesian linear model, a map of HIV prevalence was generated across the whole of Nigeria. By identifying the areas in which HIV is most prevalent interventions can be targeted. This less resource intense Bayseian method allows for national monitoring of HIV prevalence.
Elsevier,
Engineering Applications of Artificial Intelligence, Volume 123, August 2023
Using brain tissue from donors with Alzheimer's disease, Anderson et al. identify new links between gene regulation and disease. These regulators could represent future clinical targets or disease markers for Alzheimer's diagnosis and treatment.
Elsevier,
Free Radical Biology and Medicine, Volume 204, 1 August 2023
In vivo triple transgenic AD mouse model brains and retinas showed hypoxic vessels expressing hypoxyprobe and HIF-1α. In in vitro OGD-treated endothelial cells, HIF-1α upregulated NADPH oxidase (NOX) (i.e., Nox2, Nox4). NLRP1 protein was promoted by OGD, and such effect was blocked by downregulation of Nox4 and HIF-1α. Hypoxic endothelial cells of AD brains and retinas markedly expressed NLRP1, ASC, caspase-1, and interleukin-1β (IL-1β). Chronic hypoxia in microvascular endothelial cells leads to HIF-1α-NLRP1 circuit in AD.
Elsevier, The Lancet Regional Health - Europe, Volume 31, August 2023
Background: Air pollution, road traffic noise, and green space are correlated factors, associated with risk of stroke. We investigated their independent relationship with stroke in multi-exposure analyses and estimated their cumulative stroke burden. Methods: For all persons, ≥50 years of age and living in Denmark from 2005 to 2017, we established complete address histories and estimated running 5-year mean exposure to fine particles (PM2.5), ultrafine particles, elemental carbon, nitrogen dioxide (NO2), and road traffic noise at the most, and least exposed façade.
Elsevier,
Journal of Cleaner Production, Volume 412, 1 August 2023
This review assessed the academic landscape on the use of ANN for Smart Cities towards SDG-11. A keyword-based methodological framework was used to retrieve the relevant documents. The documents were assessed using descriptive and content analysis. Results revealed significant research interest on the topic and is on an increasing trend. Research works on the topic are expected to increase as clusters on specific topics have formed. This review identified the SDG-11 themes Environmental Impact, Transport Systems, and Urbanization among the most prominent. Research gaps were identified in the SDG-11 themes on Green and Public Spaces, and Natural and Cultural Heritage.