This review attempts to shed more light on the prevalence of depression in Sub-Saharan Africa (SSA), its pathophysiology, risk factors, diagnosis and the experimental models available to study depression within the sub-region. It also evaluates the contribution of the sub-region to the global research output of depression as well as bottlenecks associated with full exploitation of the sub region’s resources to manage the disorder.
Background: Over 85% of Kibera's population, an informal settlement in Nairobi, Kenya, is food insecure. Nutrition-sensitive agriculture interventions, such as sack gardens, have the potential to diversify diets - in turn, improving household food security and diet quality. Furthermore, the sale of extra vegetables may provide an income for program participants. Objectives: The aim of this paper was to conduct a feasibility assessment and preliminary impact assessment of a nutrition-sensitive urban agriculture intervention that used sack gardens for women in Kibera.
Exercise to Prevent and Manage Chronic Disease Across the Lifespan, 2022, Pages 413-421
This book chapter advances SDG #3 and #10 by outlining the pathophysiology associated with Alzheimer’s disease and provide an overview of the impact of exercise programs on cognition, physical functional abilities, behavioral, and psychological symptoms and quality of life.
This chapter advances SDG goals 6 and 11 by focussing on Kenya's inland, coastal and marine resources, and their associated stressors and threats to ecological integrity. It provides key recommendations to promote societal benefits and enhance sustainable management of these aquatic resources.
This chapter aligns with Goal 11: Sustainable Cities and Communities and 6: Clean Water and Sanitation by reviewing Kenya's inland, coastal and marine resources, their associated stressors and key recommendations to promote societal benefits and enhance sustainable management of these aquatic resources.
This Article supports SDGs 3, 5, and 10 by evaluating the safety and efficacy of injectable cabotegravir versus daily oral tenofovir diphosphate plus emtricitabine for HIV prevention in HIV-uninfected women across sub-Saharan Africa.
An Article in support of SDG 3, evaluating conditions under which risk-informed pre-exposure prophylaxis use would be cost-effective in sub-Saharan Africa.
Neurobiology of Brain Disorders (Second Edition), Biological Basis of Neurological and Psychiatric Disorders, 2022, Pages 313-336
This book chapter advances SDG #3 and #10 by reviewing several key topics that influence our understanding of pathogenic mechanisms and lead to the identification of novel therapeutic strategies. These include the diagnostic spectrum of MCI and AD, genetic risk alleles associated with late-onset AD, structures of gamma-secretase and tau, imaging and fluid biomarkers, the role of microglia and neuroinflammation, and novel animal models of AD.
An Article in support of SDGs 2 and 15, showing that farm-level diversification might contribute to improved nutrition among children and other target groups in some but not all situations, but livestock production seems to be conducive for improving child and adolescent nutrition on average.
This study demonstrates that a multipronged SBCC (social and Behavior Change Communication) intervention can modify mothers’ complementary feeding practices, improve fathers’ and mothers’ knowledge of complementary feeding, and increase fathers’ support for complementary feeding, despite low levels of participant-reported exposure to some intervention components.
