The role of science in achieving the United Nations' Sustainable Development Goals (SDGs) cannot be overstated. Science, technology, and innovation are instrumental to addressing the significant challenges encompassed within the 17 SDGs, ranging from poverty and inequality to climate change and biodiversity loss.

Science underpins our understanding of the challenges our world faces and is pivotal in SDG 13 (Climate Action) and SDG 14 (Life Below Water) and 15 (Life on Land), where understanding ecosystems, environmental degradation, and climate change is paramount. Research in the Earth and environmental sciences provides us with knowledge about the severity of these issues and potential mitigation and adaptation strategies.

Furthermore, in SDG 3 (Good Health and Well-being), science in the form of medical research and biotechnology contributes to the development of treatments and preventive measures for various diseases. Vaccines, therapeutic drugs, and disease prevention techniques have been made possible due to advancements in biological and health sciences.

Moreover, technological advancements and innovative solutions, often rooted in science, are essential to achieving SDG 7 (Affordable and Clean Energy), SDG 6 (Clean Water and Sanitation), and SDG 9 (Industry, Innovation, and Infrastructure). From developing renewable energy technologies to creating systems that enhance water and sanitation accessibility, science serves as the bedrock of these innovations.

Science also plays a critical role in SDG 2 (Zero Hunger) by improving agricultural methods, crop yields, and food storage. Through genetic engineering and modern farming techniques, scientists can help increase food security and reduce world hunger.

Finally, science is integral to SDG 4 (Quality Education). A well-rounded education should include a robust scientific curriculum that fosters critical thinking, problem-solving, and a deep understanding of the world. Furthermore, by promoting scientific literacy, societies are better equipped to make informed decisions about policies and practices that affect sustainable development.

To make strides in achieving the SDGs, the scientific community, policymakers, and society must work together. The integration of science into policy-making processes is fundamental in developing and implementing sustainable and impactful strategies that move us closer to accomplishing these ambitious yet achievable goals.

Alzheimer's disease (AD) is considered a polygenic disorder. This view is clouded, however, by lingering uncertainty over how to treat the quasi “monogenic” role of apolipoprotein E (APOE). The APOE4 allele is not only the strongest genetic risk factor for AD, it also affects risk for cardiovascular disease, stroke, and other neurodegenerative disorders. This review, based mostly on data from human studies, ranges across a variety of APOE-related pathologies, touching on evolutionary genetics and risk mitigation by ethnicity and sex.
Illustration of process for haplotype-specific reporter construct derivation.
This Article supports SDG 3 by analysing data from four international cohorts of patients with pulmonary arterial hypertension, a disease caused by rare genetic variants.
Elsevier, Trends in Ecology and Evolution, Volume 34, February 2019
There is worldwide concern about the environmental costs of conventional intensification of agriculture. Growing evidence suggests that ecological intensification of mainstream farming can safeguard food production, with accompanying environmental benefits; however, the approach is rarely adopted by farmers. Our review of the evidence for replacing external inputs with ecosystem services shows that scientists tend to focus on processes (e.g., pollination) rather than outcomes (e.g., profits), and express benefits at spatio-temporal scales that are not always relevant to farmers.
Background: Across countries and disciplines, studies show male researchers receive more research funding than their female peers. Because most studies have been observational, it is unclear whether imbalances stem from evaluations of female research investigators or of their proposed research. In 2014, the Canadian Institutes of Health Research created a natural experiment by dividing investigator-initiated funding applications into two new grant programmes: one with and one without an explicit review focus on the calibre of the principal investigator.