Elsevier,
Redox Biology, Volume 34, July 2020
Neurodegenerative diseases (NDD) such as Alzheimer's (AD) and Parkinson's disease (PD) are distinct clinical entities; however, the aggregation of key neuronal proteins, presumably leading to neuronal demise appears to represent a common mechanism. It has become evident that advanced glycation end products (AGEs) trigger the accumulation of such modified proteins, which eventually contributes to the pathological aspect of NDDs. Increased levels of AGEs are found in amyloid plaques in AD brains and in both advanced and early PD (incidental Lewy body disease). The molecular mechanisms by which AGE dependent modifications may modulate the susceptibility towards NDDs, however, remain enigmatic and it is unclear whether AGEs may serve as biomarker of NDD. This study detected differential associations between NDD, sex and oxidative stress markers.
Elsevier, Current Opinion in Food Science, Volume 33, June 2020
Sensory and consumer researcher can focus on the three main topics exemplified in this short review: corporate and consumer social responsibility, low income or vulnerable consumers, and migration. The concept of corporate and consumer social responsibility has gained more and more attention as people attempt to understand the relationship between the effort made by industry to carry out social and environmental actions.
Elsevier, Biological Conservation, Volume 246, June 2020
The destruction of natural habitats is causing loss of biodiversity and ecosystem services. Although a “zero deforestation” is targeted, agriculture expansion caused by increasing human population and per capita consumption might boost the destruction of natural habitats in the coming decades. Here, we estimated the current and future extinction crisis in terrestrial ecoregions caused by habitat destruction and related this pattern with the current conservation efforts.
Elsevier, Neurobiology of Disease, Volume 139, June 2020
Objectives: The mechanisms leading to neurodegeneration in Alzheimer's disease (AD) may involve oxidative stress and neuroinflammation. Ceruloplasmin (Cp) is a circulating protein that intersects both these pathways, since its expression is increased during the acute phase response, and the protein acts to lower pro-oxidant iron in cells. Since the role of Cp in AD, and its potential for use as a biomarker is not established, we investigated CSF Cp and its association with longitudinal outcome measures related to AD.
Elsevier, Asian Journal of Psychiatry, Volume 51, June 2020
At the start of 2020, the 2019 coronavirus disease (COVID-19), originating from China has spread to the world. There have been increasing numbers of confirmed cases and deaths around the globe. The COVID-19 pandemic has paved the way for considerable psychological and psychosocial morbidity among the general public and health care providers. An array of guidelines has been put forward by multiple agencies for combating mental health challenges. This paper addresses some of the mental health challenges faced by low and middle income countries (LMIC).
Elsevier, Current Research in Green and Sustainable Chemistry, Volume 3, June 2020
Obesity represents an important public health concern because it substantially increases the risk of multiple chronic diseases and thereby contributing to a decline in both quality of life and life expectancy. Besides unhealthy diet, physical inactivity and genetic susceptibility, environmental pollutants also contribute to the rising prevalence of obesity epidemic.
Elsevier, Current Opinion in Green and Sustainable Chemistry, Volume 23, June 2020
To be socially accepted widely, the emerging circular bioeconomy needs to rely increasingly on residual bio-based feedstock and waste, hence reducing its dependency on crops which are in competition with agriculture/food markets. Food waste represents a valuable option as it allows for the production of a wide range of bio-based products ranging from biofuels to bioplastics. First successful experiences have shown that the involvement of stakeholders with different behaviours, values and backgrounds is a key enabler of the process.
Repair of injured skeletal muscle is a sophisticated process that uses immune, muscle, perivascular, and neural cells. In acute injury, the robust endogenous repair process can facilitate complete regeneration with little to no functional deficit. However, in severe injury, the damage is beyond the capacity for self-repair, often resulting in structural and functional deficits. Aside from the insufficiencies in muscle function, the aesthetic deficits can impact quality of life.
