Articles

Elsevier, Advances in Radiation Oncology, Volume 5, 1 September 2020
Purpose: Poor nutrition is highly implicated in the pathogenesis of cancer and affects the survival of patients during and after completion of definitive therapies. Mechanistic evidence accumulated over the last century now firmly places dysregulated cellular energetics within the emerging hallmarks of cancer. Nutritional intervention studies often aim to either enhance treatment effect or treat nutritional deficiencies that portend poor prognoses.
Elsevier, Materials Today Sustainability, Volume 9, September 2020
CeO2 shows unique catalytic properties by an acid–base bifunctionality as well as redox properties. The acid–base bifunctional properties of CeO2 have been applied to the non-reductive CO2 conversion with alcohols such as dimethyl carbonate (DMC) synthesis from CO2 and methanol. CeO2 shows very high selectivity to DMC; however, the yield of DMC is strongly limited by the equilibrium. The combination of the synthesis of organic carbonates from CO2 and corresponding alcohols with suitable H2O removal methods can enhance the yield of the organic carbonates beyond the equilibrium limitation.
Elsevier, Materials Today Sustainability, Volume 9, September 2020
Manufacturing challenges are anticipated to become worse in the coming decades owing to global material and energy constraints combined with environmental issues associated with conventional processes. Addressing these difficulties calls for a significant amount of research to be conducted to establish robust new technologies that are cost-effective and energy efficient, while at the same time minimizing environmental pollution.
Elsevier, Materials Today Sustainability, Volume 9, September 2020
Solar light-driven water splitting provides a promising way to store and use abundant solar energy in the form of gaseous hydrogen which is the cleanest chemical fuel for mankind; therefore this field has been attracting increasing attention over the past decades.
Elsevier, Physiology and Behavior, Volume 223, 1 September 2020
Alzheimer's disease (AD) is associated with cognitive deficits and behavioral disorders such as anxiety and depression. Recent clinical and experimental studies have demonstrated that swimming exercise could be a potential therapy for cognitive and behavioral disorders. The prevalence of anxiety and depression is increasing among patients with AD; hence, further studies are needed to develop therapies for these behavioral abnormalities.
Elsevier, EBioMedicine, Volume 59, September 2020
Background: Cholinergic neuronal loss is one of the hallmarks of AD related neurodegeneration; however, preclinical promise of α7 nAChR drugs failed to translate into humans. CHRFAM7A, a uniquely human fusion gene, is a negative regulator of α7 nAChR and was unaccounted for in preclinical models. Methods: Molecular methods: Function of CHRFAM7A alleles was studied in vitro in two disease relevant phenotypic readouts: electrophysiology and Aβ uptake. Genome edited human induced pluripotent stem cells (iPSC) were used as a model system with the human context.
Elsevier, EBioMedicine, Volume 59, September 2020
Background: Recently, we reported that patients with mild cognitive impairment (MCI) harbor specific signature of bacteria in their gut and that a modified Mediterranean ketogenic diet (MMKD) improves Alzheimer's disease (AD) markers in cerebrospinal fluid (CSF) and the signatures of gut bacteria. However, other microbial population such as gut fungi (mycobiome) in relation to MCI/AD pathology, gut bacteria and diet remain unknown.
Elsevier,

Biomedical Signal Processing and Control, Volume 62, September 2020

Objective imaging-based biomarker discovery for psychiatric conditions is critical for accurate diagnosis and treatment. Using a machine learning framework, this work investigated the utility of brain's functional network topology (complex network features) extracted from functional magnetic resonance imaging (fMRI) functional connectivity (FC) as viable biomarker of autism spectrum disorder (ASD). To this end, we utilized resting-state fMRI data from the publicly available ABIDE dataset consisting of 432 ASD patients and 556 matched healthy controls.

Elsevier,

Transportation Research Part A: Policy and Practice, Volume 139, September 2020

Although the last decades have seen an advance in equality and empowerment for women, there are still numerous challenges to be addressed. Among them, and particularly pressing in cities, are issues of gender-based violence, including sexual harassment in public spaces. Despite the numerous effects that street harassment has on women, and the high incidence of it in different countries, this issue has not been broadly studied, and even less so in cities in the Global South.

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