Elsevier,
Neuroscience Letters, Volume 836, 27 July 2024
This article discusses the impact of methionine oxidation on clusterin function in Alzheimer's disease, highlighting the elevated levels of MetO-clusterin in human and mouse brains affected by the disease, and how this oxidation compromises clusterin's chaperone function, potentially exacerbating beta-amyloid toxicity in Alzheimer's pathology.
Elsevier,
Acta Pharmaceutica Sinica B, Volume 14, July 2024
The study discusses the latest developments in Alzheimer’s disease treatment, with a focus on monoclonal antibodies and aptamers. It covers the current state of therapies, recent drug approvals, and future perspectives on immunotherapeutic strategies.
Elsevier,
Neuropharmacology, Volume 252, 1 July 2024
Every year, 10 million people develop dementia, most commonly Alzheimer's disease (AD), and despite limited therapies and no prevention for cognitive decline, this review offers a neuroimmunological perspective on AD progression, focusing on the role of the NLRP3 inflammasome, its brain triggers, and the potential impact of various NLRP3 inhibitors currently under investigation in preclinical and clinical trials.
Elsevier,
Engineering Applications of Artificial Intelligence, Volume 133, July 2024
With evident relevance to SDG 6, the research explores a water pollution control technology evaluation model based on the Pythagorean language neutrosophic set (PLNS) in the context of the pulp and paper industry. The authors' model aims to assist in the choice of appropriate water pollution control technology for those working within the paper industry. It is tested in an example based in China.
Elsevier,
Neuroscience Research, Volume 204, July 2024
This study found that Alzheimer’s disease neuropathological change (ADNC) is associated with gene expression changes that may impair cholesterol biosynthesis in neurones but not astrocytes, whilst levels of cortical cholesterol show a weak relationship to dementia status.
Elsevier,
The Lancet Regional Health - Western Pacific, Volume 48, July 2024
This Article supports SDG 3 by assessing the effectiveness of a hepatitis B model of care in Australia, suggesting that the model, involving primary health care, could be rolled out nationally or internationally. The authors suggest that the model could have positive implications particularly for low-income and middle-income countries.
Elsevier,
The Lancet Regional Health - Americas, Volume 35, July 2024
This Article supports SDG 3 by evaluating a hepatitis B screening programme in which members of the West African community in the Bronx were offered hepatitis B testing when they attended a blood pressure clinic visit following an educational intervention about hypertension. Almost all participants accepted to have hepatitis B screening, showing the effectiveness of its being linked to blood pressure testing.
