Elsevier,
Brain Research, Volume 1838, 1 September 2024
The study demonstrates that the peptide PHDP5, which inhibits dynamin-MT interaction, can rescue impaired endocytosis and synaptic transmission caused by tau in presynaptic terminals. When administered intranasally to Alzheimer's disease (AD) model mice, PHDP5 significantly improved learning and memory, suggesting its potential as a candidate for human AD therapy.
Elsevier,
Pharmacological Research - Modern Chinese Medicine, Volume 12, September 2024
The study investigates the neuroprotective effects of hordenine against AlCl3-induced Alzheimer’s disease in rats. Results show that hordenine improves memory and cognitive functions, suggesting its potential to reverse oxidative stress and neuroinflammation associated with Alzheimer’s
Elsevier,
Journal of Neuroscience Methods, Volume 409, September 2024
Despite significant investment, effective treatments for Alzheimer's disease (AD) have been elusive, necessitating improved quality and reproducibility of foundational laboratory evidence; to address this, AD-SOLES, an integrated workflow of automated tools and a publicly accessible interactive dashboard, has been developed to collect, curate, and visualize in vivo experimental evidence, enhancing evidence synthesis, tracking reporting quality, and aiding researchers in locating relevant data.
Elsevier,
iScience, Volume 27, 20 September 2024
In this study, the authors estimate the causal effect of air pollution on eye and ear health. They find that eye or ear disease possibility rises 1.48% for a 10 μg/m3 increase in four-week average PM2.5 concentration. The impacts can last about 28 weeks and will be insignificant afterward.
Elsevier,
Advances in Nutrition, Volume 15, September 2024
The article systematically reviews research linking climate change to food systems, nutrition, and health (FSNH) from 2018-2023. It identifies key research gaps and presents an Evidence and Gap Map (EGM) to visualize the current landscape. Most studies focus on climate impacts on crop and livestock production, while fewer address nutrition-related health and postharvest processes. Addressing these gap is critical for developing effective climate adaptation and mitigation strategies that promote both human and planetary health.
Elsevier,
Carbon Capture Science and Technology, Volume 12, September 2024
This text ties into several Sustainable Development Goals (SDGs), particularly SDG 12 (Responsible Consumption and Production) and SDG 13 (Climate Action). It highlights the potential of lignin as a sustainable material that can reduce reliance on traditional plastics and contribute to carbon fixation, promoting circularity and environmental sustainability.