Articles

As one of the most food-insecure countries of the Global South, Ethiopia has experienced significant land-use changes driven by economic development and population growth. This study examined the dynamic land use transitions in Ethiopia during the period 2000–2020 including the socio-economic factors driving land-use transitions and grain demand. Although the sustained growth in international trade coupled with increased productivity has benefited the country's food supply, the food security situation in low-income countries, including Ethiopia, will remain critical in the context of population growth.

This study explores the integration of Generative Artificial Intelligence (GenAI) in water distribution networks, identifying opportunities for enhancing information retrieval, improving water quality management, implementing predictive maintenance, and optimizing operations, while also addressing challenges related to data quality, scalability, and the need for expertise in both engineering and AI, ultimately providing insights for water utilities and policymakers on leveraging GenAI responsibly.

The article discusses the potential of neuron-derived extracellular vesicles (NDEVs) as diagnostic biomarkers for Alzheimer's disease (AD). NDEVs carry pathological proteins like amyloid-? and Tau, and their levels in bodily fluids can distinguish AD patients from healthy controls and predict disease onset.

The TRAILBLAZER-ALZ 6 study found that a modified donanemab titration regimen significantly reduced ARIA-E frequency and severity compared to standard dosing, while maintaining similar amyloid reduction. Safety profiles were comparable between the two arms. The modified titration approach may help mitigate risks associated with amyloid-targeting therapies in early Alzheimer's disease.