Articles

Nuclear erythroid 2-related factor 2 (Nrf2)/Kelch-like ECH-associated protein 1 (Keap1) signalling pathway and its downstream target effects.
Elsevier,

Redox Biology, Volume 38, January 2021

Imbalances in redox homeostasis can result in oxidative stress, which is implicated in various pathological conditions including the fatal neuromuscular disease Duchenne Muscular Dystrophy (DMD). DMD is a complicated disease, with many druggable targets at the cellular and molecular level including calcium-mediated muscle degeneration; mitochondrial dysfunction; oxidative stress; inflammation; insufficient muscle regeneration and dysregulated protein and organelle maintenance. Previous investigative therapeutics tended to isolate and focus on just one of these targets and, consequently, therapeutic activity has been limited. Nuclear erythroid 2-related factor 2 (Nrf2) is a transcription factor that upregulates many cytoprotective gene products in response to oxidants and other toxic stressors. Unlike other strategies, targeted Nrf2 activation has the potential to simultaneously modulate separate pathological features of DMD to amplify therapeutic benefits. Here, we review the literature providing theoretical context for targeting Nrf2 as a disease modifying treatment against DMD.
Elsevier,

Digital Geography and Society, Volume 2, January 2021

This Article supports SDG 5 in providing insights into the feminist geographies in the digital space of online gaming.
Elsevier,

Journal of Integrative Agriculture, Volume 20, January 2021

Using China Health and Nutrition Survey data, this study employs a consistent two-step quadratic almost ideal demand system model, with addressed problems of endogeneity of total expenditure and zero shares, to estimate the food demand elasticities among adults in rural areas with regard to the different income strata.
Elsevier,

Journal of Biomedical Informatics, Volume 113, January 2021

The use of smart conversational agents for the detection of neuropsychiatric disorders is an emerging and promising field of research using AI.
Elsevier, Journal of Sexual Medicine, Volume 17, December 2020
Background: Sexual dysfunction and sexual distress are common during pregnancy, but the effects of exposure to sexual violence on sexual dysfunction and sexual distress in pregnant women is unknown. Aim: The aim of this study was to determine the effects of sexual violence on female sexual dysfunction and sexual distress. Methods: This is a descriptive study. Data were collected between December 2019 and April 2020 from 605 pregnant women.
Elsevier,

Polar Science, Volume 26, December 2020

The purpose of this paper is to explore the perceptions of climate change and permafrost thaw within the inhabitants from Yakutia by collecting and analysing narratives.
Elsevier, Sustainable Materials and Technologies, Volume 26, December 2020
Buildings consume vast amounts of energy and pollute the environment in various ways. Façade is a part of building's architecture that can play a significant role in reducing energy consumption, as well as alleviating its negative environmental effects. Although using smart materials in buildings' facades can help dramatically to attain the mentioned goals, very limited studies have been conducted regarding the mentioned issues. Moreover, existing studies have investigated only a few number of smart materials simultaneously.
Elsevier, Food Quality and Preference, Volume 86, December 2020
Targeted interventions have important under-explored potential for reducing meat consumption. We hypothesized that group-specific interventions targeting reduction for reducer, moderate-hindrance, and strong-hindrance meat eaters would be effective. All participants were randomly assigned to one of three treatment conditions designed for these three meat-eating groups, or to a control condition. Following the intervention, up to 28 days of food diaries were gathered to measure their consumption of animal products, which were weighted according to their greenhouse gas emissions.
Elsevier, Food Quality and Preference, Volume 86, December 2020
Research on the relationship between vegetarianism and subjective well-being (SWB) has produced inconsistent results, which may partly be due to small sample sizes and divergent operationalizations of well-being.
Elsevier, Current Opinion in Green and Sustainable Chemistry, Volume 26, December 2020
Food waste valorization is a hot topic due to the cornucopia of waste generated and the ensuing detrimental environmental effects. Food is lost or wasted in a variety of means on its way from field to mouth. Once deemed inedible, it is considered a waste, but it still contains first-rate organic material that can be processed and used to create a host of new products, chemicals, or energy. Upgrading food wastes can be performed in a variety of processes.

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