hLife
Volume 3, Issue 5
2025
2025
This review article explores advancements in 3D models using human iPSC-derived microglia to study neurodevelopment and neurological disorders, highlighting the potential of these models to enhance understanding of microglial functions and their roles in various diseases. The article also discusses the challenges and future directions in developing more physiologically relevant brain organoid models.
This article outlines a theory of goodness, coupled with some of its practical implications for impact-making, governance and lives more generally. The theory proposes that goodness consists of positive feelings and whatever promotes them, such as the joy of a meaningful conversation or the satisfaction of eating food, for instance. Although it is a version of ethical hedonism, the theory is also called welfarism since it allocates a central role to affect and since affect is central to some prevalent measures of 'subjective wellbeing'.
This paper reviews and compares four leading healthy diet metrics: GDQS, GDR score, MDD-W, and Nova UPF score, for their accuracy, ease of use, and global applicability in monitoring dietary quality. The findings highlight that the Minimum Dietary Diversity for Women (MDD-W) offers the strongest predictive accuracy for nutrient adequacy using a simple, scalable method, while also emphasizing the need for further research on metrics assessing moderation and cross-country comparability.
Drivers of health disparities in rheumatology are numerous and complex, existing within and between populations. These impact access to advanced therapies, specialized services, and core components of care.
International Day of Sport for Development and Peace 2026: Sport as a Bridge for Inclusion and Unity
International Day of Human Space Flight 2026: A Tribute to Exploration, Unity, and Progress
22nd April is Earth Day, an annual, global movement to raise awareness and promote environmental protection. The theme for Earth Day 2025 is OUR POWER, OUR PLANET, inviting everyone around the globe to unite behind renewable energy, and to triple the global generation of clean electricity by 2030. To mark the event Elsevier has curated a free to access Special Collection featuring the latest research articles and book chapters to advance knowledge.
This perspective highlights the challenges and opportunities of implementing people-centered multi-hazard early warning systems in the Global South, emphasizing the need for localized, inclusive approaches that address vulnerability and the complex interrelationships of hazards, to bridge the gap between global ambitions and operational realities.
