Articles

This study developed a novel mouse model with tamoxifen-inducible knockout of the Gnpat gene, enabling late-onset plasmalogen deficiency to investigate its role in Alzheimer's disease. The model exhibited significant plasmalogen reduction and associated behavioral and nerve function changes, providing a valuable tool for future research on plasmalogen involvement in neurodegeneration and potential therapies.

Review on the study of active peptides in AD and PD, deals with role of inflamation, synaptic plasticity, and other learning, memory and cognitive functions related to AD

The study explores the use of a novel gene delivery system, AAV-aMTD-Parkin, to enhance motor and cognitive functions in animal models of Parkinson’s and Alzheimer’s diseases. This system improves the delivery efficiency of therapeutic proteins, potentially offering a new treatment approach for these neurodegenerative disorders.

This research examines how indigenous archaeology and how the emergence of the first urban centers in the Mongolian steppe coincided with the establishment of the Uyghur Khaganate during the mid-eighth century CE.