World Alzheimer's Day 2021: The Power of Knowledge

World Alzheimer's Day is an international campaign organised by Alzheimer's Disease International to raise awareness and highlight issues faced by people affected by dementia. It takes place every year on September 21st and is the focus of World Alzheimer's Month.

Dementia is one of the biggest challenges we face, with nearly 50 million people living with dementia worldwide. Yet 2 out of every 3 people globally believe there is little or no understanding of dementia in their countries.The impact of World Alzheimer's Month is growing, but the stigmatisation and misinformation that surrounds dementia remains a global problem. To tackle this challenge, we need to collaborate and share best practice with one another.

In support of this year’s theme – ‘Know dementia, know Alzheimer's’ - Elsevier presents a curated, open access collection of over 70 journal articles and book chapters focused on shining a light on the warning signs of dementia and the importance of a timely diagnosis.

Elsevier,

Molecular Mechanisms of Dementia, April 2019, Pages 73-112

This book chapter advances SDGs 3 and 17 by reviewing the neurochemical aspects of Alzheimer’s type of Dementia.
Elsevier,

Evidence-informed Approaches for Managing Dementia Transitions: Riding the Waves, Volume , 4 February 2020

This book chapter advances SDGs 3 and 17 by describing the prevalence of dementia in hospitalized patients, reasons for hospitalizations, and risks to older people with dementia in hospitals. Strategies for optimizing outcomes and models of care that are designed to improve care of persons with dementia and their care partners are described to assist healthcare team members working with this unique population.
Elsevier,

Neuroprotection in Autism, Schizophrenia and Alzheimer's disease, Volume , 16 October 2019

This book chapter advances SDGs 3 and 17 by reviewing a new promising neuroprotective approach to treating AZ, Tau-based therapies including tau-kinase inhibitors to acetylation inhibitors, microtubule stabilizers, aggregation inhibitors, monoclonal anti-tau antibodies or active tau vaccines. Special emphasis has been placed on the most promising therapeutic agents that have reached clinical trials.
Elsevier,

Evidence-informed Approaches for Managing Dementia Transitions: Riding the Waves, Volume , 4 February 2020

This book chapter advances SDGs 3 and 17 by introducing aspects of the lived experience, management, and epidemiology of dementia and some of the significant transitions that people with the disease and their caregivers frequently encounter.
Elsevier,

Archives of Gerontology and Geriatrics, Volume 86, January - February 2020

This research evaluated emotion regulation of autobiographical memory in Alzheimer’s disease. AD patients tend to attribute positive meaning to positive memories. They also tend to view negative memories from a less negative perspective. AD patients may positively re-interpret negative memories.
Elsevier,

Pharmacology Biochemistry and Behavior, Volume 184, September 2019

Overconsumption of foods rich in dietary advanced glycation end products (d-AGE), saturated fats and meat, have a pro-inflammatory influence on Alzheimer's disease (AD) patients brains.
Elsevier,

Journal of Steroid Biochemistry and Molecular Biology, Volume 190, June 2019

This review gives a broad perspective on the relationship between hypercholesterolemia and Alzheimer's disease (AD), cholesterol lowering therapies for AD patients and the role of oxysterols in pathological and non-pathological conditions. Also, we propose cholesterol metabolites as valuable targets for prevention and alternative AD treatments.
Elsevier,

Cortex, Volume 115, June 2019

Memory for music has attracted much recent interest in Alzheimer's disease but the underlying brain mechanisms have not been defined in patients directly. Here we addressed this issue in an Alzheimer's disease cohort using activation fMRI of two core musical memory systems.
Elsevier,

Neurobiology of Stress, Volume 10, February 2019

Sleep and circadian rhythm disruption can be a contributing factor in the pathogenesis of Alzheimer's disease (AD).
Elsevier,

Neurobiology of Stress, Volume 9, November 2018

This review discusses the effects of the diurnal cycle of cortisol on cognitive function and physical activity in older adults with and without cognitive impairment.

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