Research

Elsevier, eClinicalMedicine, Volume 46, April 2022
Background: In autoimmune hepatitis (AIH), clinical practice and treatment guidelines frequently diverge as a reflection of disease heterogeneity and challenges in achieving standardised care. We sought to explore the utility of multiparametric (mp) MR in patients with AIH, and the impact of this technology on physicians’ decision making and intended patient management. Methods: 82 AIH patients, recruited from two sites between June and November 2019 as part of an observational cohort study, underwent non-contrast MRI alongside their standard clinical investigations.
Elsevier, The Lancet Regional Health - Americas, Volume 8, April 2022
Background: Hepatitis C is a preventable and treatable disease that has been declared a public health problem. In 2012, the prevalence of HCV serum anti-bodies in the Mexican adult population aged 20 to 49 years was 0·30%. Methods: We randomly selected a probabilistic sub-sample of 12,389 adults (20+ years) from adults participating in the National Health and Nutrition Survey (ENSANUT) 2018 who provided a venous blood sample. Anti-HCV antibodies and HCV RNA were determined for this sub-sample.
Elsevier, JHEP Reports, Volume 4, April 2022
Background & Aims: HBV infects over 257 million people worldwide and is associated with the development of hepatocellular carcinoma (HCC). Integration of HBV DNA into the host genome is likely a key driver of HCC oncogenesis. Here, we utilise targeted long-read sequencing to determine the structure of HBV DNA integrations as well as full isoform information of HBV mRNA with more accurate quantification than traditional next generation sequencing platforms. Methods: DNA and RNA were isolated from fresh frozen liver biopsies collected within the GS-US-174-0149 clinical trial.
Elsevier,

The Lancet Planetary Health, Volume 6, April 2022

In the journey towards attaining the Sustainable Development Goals (SDGs), large scale organic farming has emerged as a strategy of increasing significance.
Spatial resolution of the geographical information system-based model
Elsevier,

The Lancet Planetary Health, Volume 6, April 2022

Background: Increasing air conditioner use for cooling indoor spaces has the potential to be a primary driver of global greenhouse gas emissions. Moving indoor air with residential fans can raise the temperature threshold at which air conditioning needs to be turned on to maintain the thermal comfort of building occupants. We investigate whether fans can be used to reduce air conditioner use and associated greenhouse gas emissions.

Elsevier

On April 22 every year, we celebrate the anniversary of the birth of the modern environmental movement with Earth Day. Since the first Earth Day in 1970, this day has marked global collaboration and awareness of the need to fight for a cleaner and healthier Earth. It all began in 1962 when Rachel Carson’s Silent Spring hit the New York’s bestseller list selling over 500,000 copies in 24 countries.

Elsevier, One Earth, Volume 5, 15 April 2022
Carbon capture and storage (CCS) has been recognized as a key technology in energy systems decarbonization. However, numerous attempts to deploy CCS failed, and the technology is still viewed as pre-commercial. Consequently, public investment in CCS has been largely limited to research, development, and demonstration (RD&D) in capture technology.
Elsevier,

The Lancet Global Health, Volume 10, April 2022

An Article in support of SDGs 2 and 10, analysing global inequalities in the double burden of malnutrition and its association with economic and social globalisation, showing that the probability of the double burden of malnutrition at the household level differs across country income and household wealth.

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