Elsevier, The Lancet Global Health, Volume 8, February 2020
Background: In the context of the Sustainable Development Goals and the shifting global burden of disease, this systematic review analyses the evidence from rigorously evaluated programmes that seek to transform the gendered social norms undermining the health and wellbeing of children, adolescents, and young adults.
Elsevier, The Lancet Global Health, Volume 8, February 2020
Background: Innovative solutions are required to provide mental health support at scale in low-resource humanitarian contexts. We aimed to assess the effectiveness of a facilitator-guided, group-based, self-help intervention (Self-Help Plus) to reduce psychological distress in female refugees. Methods: We did a cluster randomised trial in rural refugee settlements in northern Uganda. Participants were female South Sudanese refugees with at least moderate levels of psychological distress (cutoff ≥5 on the Kessler 6).
Elsevier, Neuron, Volume 105, 19 February 2020
The use of advanced technological solutions (“neurotechnologies”) can improve the clinical outcomes of neurorehabilitation after stroke. Here, Micera et al. propose a paradigm shift that is based on a deep understanding of the basic mechanisms of natural stroke recovery and technology-assisted neurorehabilitation to improve the clinical effectiveness of neurotechnology.
Elsevier, Remote Sensing of Environment, Volume 237, February 2020
Sustainable Development Goal (SDG) indicator 15.1.1 proposes to quantify “Forest area as a proportion of total land area” in order to achieve SDG target 15.1. While area under forest cover can provide useful information regarding discrete changes in forest cover, it does not provide any insight on subtle changes within the broad vegetation class, e.g. forest degradation. Continental or national-level studies, mostly utilizing coarse-scale satellite data, are likely to fail in capturing these changes due to the fine spatial and long temporal characteristics of forest degradation.
Elsevier, The Lancet, Volume 395, 22 - 28 February 2020
Background: WHO is developing a global strategy towards eliminating cervical cancer as a public health problem, which proposes an elimination threshold of four cases per 100 000 women and includes 2030 triple-intervention coverage targets for scale-up of human papillomavirus (HPV) vaccination to 90%, twice-lifetime cervical screening to 70%, and treatment of pre-invasive lesions and invasive cancer to 90%. We assessed the impact of achieving the 90–70–90 triple-intervention targets on cervical cancer mortality and deaths averted over the next century.
Elsevier, The Lancet, Volume 395, 22 - 28 February 2020
Background: The WHO Director-General has issued a call for action to eliminate cervical cancer as a public health problem. To help inform global efforts, we modelled potential human papillomavirus (HPV) vaccination and cervical screening scenarios in low-income and lower-middle-income countries (LMICs) to examine the feasibility and timing of elimination at different thresholds, and to estimate the number of cervical cancer cases averted on the path to elimination.
Elsevier, Heliyon, Volume 6, February 2020
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive decline in cognitive function. Intracerebroventricular injection of streptozotocin (icv-STZ) has been used as an experimental model of Sporadic AD (SAD) in rodents and represents a promising tool for etiopathogenic analysis and evaluation of new therapeutic proposals for AD. The icv-STZ model shows many aspects of SAD abnormalities, resulting in decreased brain glucose and energy metabolism, cognitive impairment, oxidative stress, neuronal loss, and amyloid angiopathy.
Elsevier,
One Earth, Volume 2, 21 February 2020
Approximately 1 billion people currently live in informal settlements, primarily in urban areas in low- and middle-income countries. Informal settlements are defined by poor-quality houses or shacks built outside formal laws and regulations. Most informal settlements lack piped water or adequate provision for sanitation, drainage, and public services. Many are on dangerous sites because their inhabitants have a higher chance of avoiding eviction. This paper considers how to build resilience to the impacts of climate change in informal settlements.
