Threat processing is central to understanding debilitating fear- and trauma-related disorders such as posttraumatic stress disorder (PTSD). Progress has been made in understanding the neural circuits underlying the “engram” of threat or fear memory formation that complements a decades-old appreciation of the neurobiology of fear and threat involving hub structures such as the amygdala.
There have been several recent studies addressing the genetic architecture of depression. This review serves to take stock of what is known now about the genetics of depression, how it has increased our knowledge and understanding of its mechanisms, and how the information and knowledge can be leveraged to improve the care of people affected.
Elsevier, Sustainable Cities and Society, Volume 46, April 2019
This paper examines the potential of energy saving in electrical consumption if the concept of energy-efficient house is implemented in Oman. Energy consumption in the residential sector in Oman was critically analysed and forecasted based on its growth rate and its historical consumption. Then, a base-case validated simulation model for a typical residential dwelling in different cities was generated using a dynamic building simulation software, covering a wide variation of climate conditions in Oman.
The advent of more proactive consumers, the so-called “prosumers” with production and storage capabilities, is empowering the consumers and bringing new opportunities and challenges to the operation of power systems in a market environment. Recently, a novel proposal for the design and operation of electricity markets has emerged: these so-called peer-to-peer (P2P) electricity markets conceptually allow the prosumers to directly share their electrical energy and investment.
Elsevier, Biomass and Bioenergy, Volume 123, April 2019
Pyrolysis converts biomass into liquid, gaseous and solid fuels. This work reviews the existing models for biomass pyrolysis, including kinetic, network and mechanistic models. The kinetic models are based on the global reaction mechanisms and have been extensively used for a wide range of biomass under various operating conditions. Major emphases have been on the network models as these models predict the structural changes during biomass pyrolysis. Key aspects of various network models include reaction schemes, structural characteristics and applications to CFD simulations.
Elsevier, Advances in Radiation Oncology, Volume 4, April - June 2019
The proportion of female trainees in radiation oncology has generally declined despite increasing numbers of female medical students; as a result, radiation oncology is among the bottom 5 specialties in terms of the percentage of female applicants. Recently, social media has been harnessed as a tool to bring recognition to underrepresented groups within medicine and other fields.
Elsevier,
International Journal of Disaster Risk Reduction, Volume 35, April 2019
Groundwater storage (GWS) – a hidden resource underneath the land surface, plays a critical role in sustaining irrigated agriculture in these river basins, particularly during the dry season when rice crops are generally grown in irrigated lands across South Asia. Although monitoring of groundwater levels has been operational in the region for a number of decades, a basin-wide comprehensive assessment of GWS is lacking in most river basins.
Elsevier,
SLAS Technology, Volume 24, 1 April 2019
Cystic fibrosis is a genetic disease affecting more than 70,000 people worldwide. Caused by a mutation in the CFTR gene, cystic fibrosis can result in difficulty breathing, widespread bacterial infections, edema, malnutrition, pancreatitis, and death. Current drug-based treatments struggle to reach the site of action due to the thick mucus, and only manage symptoms such as blocked airways, lung infections, and limited ability to digest food. Nanotechnology opens up possibilities for improved treatment strategies by focusing on drug penetration through the mucus lining, eliminating resulting bacterial infections, and targeting the underlying genetic cause of the disease. In this review, we present recent nanoparticle developments for cystic fibrosis, challenges in nanomedicine therapeutics, and future research directions in gene editing and nonviral vectors for gene delivery.
Elsevier, Joule, Volume 3, 20 March 2019
Solar photovoltaic modules have suddenly emerged as one of the cheapest options for bulk electricity supply. In a recent Energy Policy article, Kavlak et al. (2018) describe a methodology for quantifying causes of such cost movements and apply it to photovoltaic modules. Their approach, however, overlooks the “butterfly effect” of serendipitously interacting people and events, without which photovoltaics likely would still be expensive.
Solar water disinfection catalyzed by metal-free photocatalyst has emerged as a promising approach for clean water production. By using the edge-functionalized graphitic carbon nitride (g-C3N4) as photocatalytic disinfectants, we find that the pathogen-rich water can be rapidly purified in 30 min with a disinfection efficiency of over 99.9999% under visible-light irradiation, which meets the requirement for drinking water.
